The area is located in the south of the province of Salamanca in the municipalities of Cepeda, Cristóbal, El Cerro, El Tornadizo, Garcibuey, Herguijuela de la Sierra, Lagunilla, Las Casas del Conde, Los Santos, Madroñal, Miranda del Castañar, Mogarraz, Molinillo, Monforte de la Sierra, Montemayor del Río, Pinedas, San Esteban de la Sierra, San Martín del Castañar, San Miguel de Valero, Santibáñez de la Sierra, Sequeros, Sotoserrano, Valdefuentes de Sangusín, Valdelageve, Valero and Villanueva del Conde.

Vineyards are located on terraces above the Alagón river. A part of the production area is inside the Natural Park of “Las Batuecas – Sierra de Francia” and all the area is inside the Biosphere Reserve “Sierras de Béjar – Francia”. This last title, awarded by UNESCO in 2006.

The most important grape here is the indigenous Rufete. Garnacha Tinta and Tempranillo are also approved for red wines. White grapes approved are Viura, Moscatel de Grano Menudo and Palomino.