Lagrein (pronounced lah-GRAH’EEN, lah-GRINE or lah-GRI’NE) is a red wine grape variety native to the valleys of South Tyrol, northern Italy. Along with Marzemino, it is a descendant of Teroldego, and related to Syrah, Pinot noir and Dureza.

The name suggests its origins lie in the Lagarina valley of Trentino. It was mentioned as early as in the 17th century, in records of the Muri Abbey near Bolzano.